As I understand it, arsenic is an organic compound found in some fruits (like apples) - I'm not sure it's dangerous except in large concentrations, and without some compounds found within the fruit (ie apple seeds have arsenic, so an animal eating the seeds and stopping new trees from growing would get sick, whereas an animal just eating the fruit would be safe).
I could be wrong on all of this though, so don't quote my representations as fact without more research!
Recently retired US Supreme Court Justice Souter ate an entire apple every day at lunch--including the stem, core, and seeds. (page 43, The Nine: Inside the Secret World of the Supreme Court, by CNN's Jeffrey Toobin). That's every day for many years.
Ruminents, such as deer, have a different physiology, and can safely ingest compounds that humans and domestic pets cannot. If you've never fed an apple to a horse, you're missing one of life's true joys! BTW, the horse poops out the seeds.
If you are ever out hiking in the country and run across scat (poop), try to identify the seeds that the animal (fox, skunk, porcupine, deer, etc.) pooped out. It can be quite enlightening!
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